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You are here:Home » Antibodies » Abs to Enzymes, Acetylcholinesterase » Anti -Acetylcholinesterase (ACHE, AChE)

Anti -Acetylcholinesterase (ACHE, AChE)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320kD, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170kD. Detection of higher levels of AChE in amniotic fluid can indicate fetal malformations such as neural tube defects.
Catalog #A0526-42N
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Brain (Cerebellum) lysates
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to QFDHYSKQDRCSDL, from the C-terminus of the protein sequence according to NP_000656.
SpecificityRecognizes human ACHE. Species sequence homology: mouse, rat, rabbit, feline.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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