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You are here:Home » Antibodies » Abs to Ion Channel » Anti -Acid Sensitive Ion Channel beta (ASIC beta)

Anti -Acid Sensitive Ion Channel beta (ASIC beta)

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Specifications

Clone Host Grade Applications
Polyclonal Guinea pig Serum IH
Two proton-gated channels, acid-sensing ionic channel (ASIC) and dorsal root ASIC (DRASIC), are known to be expressed by sensory neurons. These types of channels are of interest because low pH causes pain. ASIC Beta, a splice variant of ASIC, is found only in a subset of small and large diameter sensory neurons and is absent from sympathetic neurons or the central nervous system..
Catalog #A0570-50
Positive Control Rat spinal cord. Staining was blocked by preabsorption with the cognate peptide.
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGuinea pig
SourceRat
ConcentrationNot determined
FormAs reported
PuritySerum
ImmunogenResidues 3-18 of rat ASIC Beta. AGSELDEGDDSPRDLV.
SpecificityReacts with rat ASIC Beta. Species Crossreactivity: This antibody reacts with rat ASIC Beta. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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