Anti -Aconitase 1 (ACO1, ACONS, IREB1, IREBP, IREBP1, IRP1, OTTHUMP00000021176, OTTHUMP00000021177, OTTHUMP00000045233, aconitate hydratase, citrate hydro-lyase, ferritin repressor protein, iron regulatory protein 1, iron-responsive element binding protein 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B |
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| Aconitase (aconitate hydratase; EC 4.2.1.3) is an iron-sulfur protein containing an [Fe4S4]2+ cluster that catalyzes the stereospecific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle, a non-redox-active process. Tissue contains two aconitases, a mitochondrial (m-) and a cytosolic (c-) aconitase. They are related, but distinctly different enzymes and are coded for on different chromosomes. Loss of aconitase activity in cells or other biological samples treated with pro-oxidants has been interpreted as a measure of oxidative damage. | | | Catalog # | A0660-01D | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:8000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-QVDFNRRADSLQKNQ, from the internal region of human Aco1/Aconitase 1 (NP_002188.1) | | Specificity | Recognizes human Aco1/Aconitase 1. Sequence homology: mouse, rat, bovine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Aconitase 1 (ACO1, ACONS, IREB1, IREBP, IREBP1, IRP1, OTTHUMP00000021176, OTTHUMP00000021177, OTTHUMP00000045233, aconitate hydratase, citrate hydro-lyase, ferritin repressor protein, iron regulatory protein 1, iron-responsive element binding protein 1) |
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