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You are here:Home » Antibodies » Antibodies-Hormones, Steroids » Anti -ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

Anti -ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease
Catalog #A0758-07
ApplicationsSuitable for use in Immunohistochemistry, ELISA and other solid-phase assays. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: Formalin-fixed, paraffin-embedded tissue
Optimal dilutions to be determined by the researcher.
Affinity Constant>10e11 L/mole
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No1.B.55
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.6, 0.1% sodium azide
PurityPurified by Protein A affinity chromatography
SpecificityRecognizes human Synacthen (1-24 ACTH). No crossreactivity to CLIP (17-39 ACTH). Species Crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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