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You are here:Home » Antibodies » Abs to Actin Related Proteins » Anti -Actin, beta (ACTB, Actin Cytoplasmic 1, Beta Cytoskeletal Actin)

Anti -Actin, beta (ACTB, Actin Cytoplasmic 1, Beta Cytoskeletal Actin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
All eukaryotic cells express actin, which oftern constitutes as much as 50% of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one actin gene, high eukaryotes have several isoforms encoded by a family of genes. At least six types of actin are present in mammalian tissues and fall into three classes. Alpha-actin expression is limited to various types of muscle, whereas beta- and gamma-actin are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the actin cytoskeleton. Rho controls the assembly of actin stress fibers and focal adhesion. Rac regulares actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
Catalog #A0760-40P
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid.
PurityPurified by Immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to amino-terminal residues of human B-actin coupled to KLH.
SpecificityRecognizes endogenous levels of total human beta Actin. Species Crossreactivity: mouse, rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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