You are here:Home
»
Antibodies
»
Abs to Transcription Factors
»
Anti -ATF2, Phosphorylated (Thr71) (Cyclic AMP-dependent Transcription Factor ATF-2, cAMP-dependent Transcription Factor ATF-2, Activating Transcription Factor 2, Cyclic AMP-responsive Element-binding Protein 2, CREB-2, cAMP-responsive Element-binding Protein 2
Anti -ATF2, Phosphorylated (Thr71) (Cyclic AMP-dependent Transcription Factor ATF-2,
cAMP-dependent Transcription Factor ATF-2, Activating Transcription Factor 2, Cyclic
AMP-responsive Element-binding Protein 2, CREB-2, cAMP-responsive Element-binding Protein
2
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH |
|
| The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 by stress-activated kinases is necessary for transcriptional activation. Myc also induces phosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 also functions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B and H4 in vitro. | | | Catalog # | A0855-44U | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1-4ug/ml | | Immunoprecipitation: 10ug/ml | | Immunohistochemistry: 20ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | LgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% thimerosal, 50% glycerol. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to Thr71 from human ATF2. | | Specificity | Recognizes human ATF-2 when phosphorylated at Thr71. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
