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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -Activating Transcription Factor 3 (ATF3, ATF-3, Cyclic AMP-dependent Transcription Factor ATF-3, cAMP-dependent Transcription Factor ATF-3)

Anti -Activating Transcription Factor 3 (ATF3, ATF-3, Cyclic AMP-dependent Transcription
Factor ATF-3, cAMP-dependent Transcription Factor ATF-3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Catalog #A0855-58E
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG3, k
Clone No6B8
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length recombinant corresponding to aa1-181 from human Activating Transcription Factor 3 (AAH06322) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human Activating Transcription Factor 3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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