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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -Activating Transcription Factor 4 (ATF4, Tax-responsive Enhancer Element B67)

Anti -Activating Transcription Factor 4 (ATF4, Tax-responsive Enhancer Element B67)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).
Catalog #A0855-69B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide with sequence EEVRKARGKKRVP, representing the C-Terminus of the human protein (residues 339-351) according to NP_001666.
SpecificitySpecies Crossreactivity: Crossreacts with Human. Expected to crossreact with Rat and Mouse due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCyclic AMP Dependent Transcription Factor ATF4, Cyclic AMP Response Element Binding Protein 2, CREB2, DNA Binding Protein TAXREB67, TXREB


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