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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -ATF4 (S245) (Activating Transcription Factor 4 (Tax-responsive Enhancer Element B67), Activating Transcription Factor 4 (Tax-responsive Enhancer Element B67), Isoform CRA_a, , ATF4 Protein, hCG_41721)

Anti -ATF4 (S245) (Activating Transcription Factor 4 (Tax-responsive Enhancer Element
B67), Activating Transcription Factor 4 (Tax-responsive Enhancer Element B67), Isoform
CRA_a, , ATF4 Protein, hCG_41721)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). ATF4 belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain.
Catalog #A0855-69E
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acid residues surrounding S245 of human ATF4 (KLH).
SpecificityRecognizes human ATF4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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