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Anti -ATF4, phosphorylated (Ser245) (Activating Transcription Factor 4, Tax-responsive Enhancer Element B67, Cyclic AMP-dependent Transcription Factor ATF-4, cAMP-dependent Transcription Factor ATF-4, Cyclic AMP-responsive Element-binding Protein 2, CREB-2, cAM
Anti -ATF4, phosphorylated (Ser245) (Activating Transcription Factor 4, Tax-responsive
Enhancer Element B67, Cyclic AMP-dependent Transcription Factor ATF-4, cAMP-dependent
Transcription Factor ATF-4, Cyclic AMP-responsive Element-binding Protein 2, CREB-2, cAM
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| ATF4 encodes a cAMP response element (CRE) binding protein called CREB-2 which acts as a transcriptional activator. The protein contains a COOH-terminal leucine-zipper motif and an adjacent basic domain. The protein is expressed ubiquitously in human brain and umbilical vein endothelial cell. The protein binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. The protein is localized in the 22q13.1 region of human chromosome. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. ATF4 negatively regulate transcription from the cAMP response element. | | | Catalog # | A0855-69N | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to human ATF4 around the phosphorylation site of serine 245 (N-R-SP-L-P). | | Specificity | Recognizes human ATF4, phosphorylated at Ser245. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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