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Anti -Activating Transcription Factor 4 (ATF4, Tax-responsive Enhancer Element B67, Cyclic AMP-dependent Transcription Factor ATF-4, cAMP-dependent Transcription Factor ATF-4, Cyclic AMP-responsive Element-binding Protein 2, CREB-2, cAMP-responsive Element-bind
Anti -Activating Transcription Factor 4 (ATF4, Tax-responsive Enhancer Element B67, Cyclic
AMP-dependent Transcription Factor ATF-4, cAMP-dependent Transcription Factor ATF-4,
Cyclic AMP-responsive Element-binding Protein 2, CREB-2, cAMP-responsive Element-bind
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
|
| ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). ATF4 belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. | | | Catalog # | A0855-69P | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic non-phosphopeptide corresponding to human ATF4 around the phosphorylation site of serine 245 (N-R-SP-L-P). | | Specificity | Recognizes human ATF4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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