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You are here:Home » Antibodies » Abs to Enzymes » Anti -AID (AICDA, Activation-induced Cytidine Deaminase, Cytidine Aminohydrolase)

Anti -AID (AICDA, Activation-induced Cytidine Deaminase, Cytidine Aminohydrolase)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Catalog #A0855-75V
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:4000
Western Blot: 0.1-0.3ug/ml, observed in human lymph node, spleen and tonsil lysates on ~26kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to RRKFLYQFKNVR-C, from human AID, at N-terminal (NP_065712.1).
SpecificityRecognizes human AID. Species sequence homology: Bovine and porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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