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You are here:Home » Antibodies » Abs to Activin » Anti -Activin B

Anti -Activin B

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B N
Activin B is a TGF-b family member that exhibits a wide range of biological activities including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-b family, signals through the ActRII receptor (Activin Receptor type II). Human Activin B is a 26.0kD disulfide-linked homodimer consisting of two bB chains, each containing 115 amino acid residues.
Catalog #A0855-89B
ApplicationsSuitable for use in Neutralization, ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.5-1.0ug/ml. The detection limit is ~0.1ng/well.
Western Blot: 1-2ug/ml. The detection limit is ~0.5ng/lane and 1ug/lane under non-reducing and reducing conditions.
Neutralization: ~5-20ug/ml to neutralize 7.5ng/ml of human Activin AB on K562 cells.
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma with B cells obtained from a mouse
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9H17
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 5% trehalose.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to human Activin B expressed in CHO cell.
SpecificityRecognizes human Activin B.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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