Anti -Activin A Receptor type IB (ACVR1B, Activin Receptor-like Kinase 4, Activin Receptor
Type 1B Precursor, ACTR-IB, ACVRLK4, ALK4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E FC |
|
| Activin RIB, also known as activin-like kinase 4 (ALK-4), is a transmembrane serine/threonine kinase that complexes with Activin type II receptors, Activin RII or Activin RIIB, to form the heteromeric signaling complex. Several members of the TGF-beta family, including the various Activins, Nodal, and GDF-1, have been shown to signal via the Activin RIB and Activin RII/IIB complex. | | | Catalog # | A0855-90E | | Applications | Suitable for use in ELISA and Flow Cytometry. Other applications not tested. | | Recommended Dilution | ELISA: 0.5-1ug/ml | | Flow Cytometry: 25ug/ml, 10ul labels 1-2.5 x 10e5 cells in 100-200ul | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Mouse myeloma cells with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human Activin type I receptor IB extracellular domain (aa24-126). | | Storage and Stability | Lyophilized powder may be stored at -20°C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2B | | Clone No | 9L800 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Purified, NS0-derived, recombinant human Activin type I receptor IB extracellular domain (aa24-126; Accession # P36896). | | Specificity | Recognizes human RIB. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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