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You are here:Home » Antibodies » Abs to Activin Receptors » Anti -Activin A Receptor, Type II-like Kinase 2 (Activin A Receptor Type I, ACVR1, ACTRI, ACVRLK2, ALK2, FOP, SKR1, hydroxyalkyl-protein kinase)

Anti -Activin A Receptor, Type II-like Kinase 2 (Activin A Receptor Type I, ACVR1, ACTRI,
ACVRLK2, ALK2, FOP, SKR1, hydroxyalkyl-protein kinase)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Catalog #A0855-91C
Activin A receptor, type II-like 1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1 is most highly expressed in human placenta and lung. ACVRL1 deficiency causes hemorrhagic telangiectasia type 2 (HHT2; MIM 600376) also known as Rendu-Osler-Weber syndrome 2 (ORW2). Note ACVRL1 is also known as ALK1-not to be confused with the similarly named ALK (anaplastic lymphoma kinase).
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:128000
Western Blot: 0.3-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human ACVR1.
SpecificityRecognizes human ACVR1 at ~60kD in human umbilical cord lysates (calculated MW of 57.2kDa according to NP_001096.1). Species Crossreactivity: canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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