Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Activin Receptors » Anti -Activin Receptor Type IIA (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2) (APC)

Anti -Activin Receptor Type IIA (Activin Receptor Type-2A, Activin Receptor Type IIA,
ACTR-IIA, ACTRIIA, ACVR2A, ACVR2) (APC)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Activin isoforms and other members of the TGF-B superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine threonine kinase receptor, both of which are essential for signal transduction. To date, seven type I and five type II receptors, including the two type I and the two type II activin receptors, designated ActRI(A), ActRIB, ActRII(A) and ActRIIB, have been cloned from mammals. Activin type II receptors are highly conserved. Human, mouse and rat type II activin receptors share greater than 98% aa sequence homology. Recombinant soluble activin type II receptors bind activin with high affinity, and are potent activin antagonists.
Catalog #A0856-05F
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Excitation 620-650nm
Emission 660-670nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No12K5
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to human Activin Receptor IIA extracellular domain expressed in SF-21 cells.
SpecificityRecognizes human Activin RIIA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links