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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -AIB 1 (Amplified in Breast Cancer-1)

Anti -AIB 1 (Amplified in Breast Cancer-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
AIB1-AC3 recognizes AIB1, a member of the SRC-1 family of nuclear receptor coactivators with an apparent molecular weight of 160kD. The AIB1 gene has been mapped to region 20q12 and has been shown to be amplified in breast tumors and pancreatic cancer cell lines. AIB 1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation.
Catalog #A0857-07
Applications
Suitable for use in Western Blot. Other applications have not been tested.
Recommended DilutionWestern Blot: 1-5 mg/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No4i291
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4.
PurityPurified by Protein G chromatography. ~95% as determined by SDS-PAGE.
ImmunogenA synthetic peptide to the C-terminal end of human AIB1 conjugated to KLH. Molecular weight: 160kD.
SpecificityRecognizes human AIB 1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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