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You are here:Home » Antibodies » Abs to Centrosomal Proteins » Anti -ARP1 homolog A (ACTR1A, Actin-Related Protein 1 Homolog A, Centractin alpha (yeast), Actin-RPV, Alpha-Centractin, ARP1, Centractin, Centrosome-associated Actin Homolog, CTRN1)

Anti -ARP1 homolog A (ACTR1A, Actin-Related Protein 1 Homolog A, Centractin alpha (yeast),
Actin-RPV, Alpha-Centractin, ARP1, Centractin, Centrosome-associated Actin Homolog,
CTRN1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
his gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Catalog #A0857-40C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:8000
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in Tris-saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide of ARP1.
SpecificityRecognizes ARP1 at ~45kD in human brain lysates (predicted MW of 43kD according to NP_005727). This epitope was selected to minimise the chance of cross-reactivity with ACTR1B (YEEDGSRAIHRKT). Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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