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You are here:Home » Antibodies » Abs to Proteins » Anti -ACTR1B (ARP1, ARP1B, Centractin Beta (Yeast), CTRN2, PC3, Yeast Homolog B)

Anti -ACTR1B (ARP1, ARP1B, Centractin Beta (Yeast), CTRN2, PC3, Yeast Homolog B)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
In addition to conventional actins, there are several actin-related proteins. The ACTR1B protein and the ACTR1A protein are of equal length, and they share 90% amino acid identity and 96% amino acid similarity. ACTR1B is expressed in the cytosol as part of the dynactin complex. The dynactin complex has been shown to localize to multiple structures within the cell, including membrane organelles, the centrosome, spindle poles, and spindle pole microtubules during mitosis and prometaphase kinetochores. It regulates dyneinmediated vesicle movement on microtubules as well as spindle assembly and cell division. ACTR1B appears to be ivolved in dynein-driven vesicle movement.
Catalog #A0857-43
Cellular Localization Cytoplasmic
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:128000.
Western Blot: 0.5-2ug/ml. Predicted molecular weight 45kD. Detects a band of ~ 43kD.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: YEEDGSRAIHRKT representing the C terminus of the human protein (residues 363-375),according to NP_005726.
SpecificityThis antibody may crossreact with ACTR1A. Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse and Rat due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesARP1, ARP1B, Centractin Beta (Yeast), CTRN2, PC3, Yeast Homolog B


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