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You are here:Home » Biochemicals » Biochem-Antibiotics » Acyclovir (Zovirax, Acycloguanosine)

Acyclovir (Zovirax, Acycloguanosine)

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Specifications

Acyclovir (Zovirax) is classified as an antiviral used in the treatment of Herpes genitalis, herpes simplex, herpes zoster and other diseases. Acyclovir inhibits the replication of viral DNA needed to reproduce itself. Phosphorylation by herpes simplex virus thymidine kinase (HSV-TK) leads to the formation of acycloguanosine triphosphate that competitively inhibits the viral DNA polymerase. Acycloguanosine can be used to induce apoptosis in cells transfected with HSV-TK. Inhibits replication of cytomegalovirus by a mechanism that is independent of its phosphorylation by viral or cellular thymidine kinase.
Catalog #A0858-50
Absorption Coefficient 603-641
Loss on Drying 6%
Related Substances 1%
Heavy Metals 0.001%
Residue of Ignition 0.1%
Storage & StabilityMay be stored at 4°C. Stable for at least 12 months.
CAS Number59277-89-3
Molecular FormulaC8H11N5O3
Molecular Weight225.2
Purity98-101%
FormWhite to off white crystalline powder
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAcycloguanosine; 9-[(2-Hydroxyethoxy)methyl]guanine


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