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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM 8 (ADAM8, a Disintegrin and Metalloproteinase Domain 8, MS2, CD156, CD156 MS2)

Anti -ADAM 8 (ADAM8, a Disintegrin and Metalloproteinase Domain 8, MS2, CD156, CD156 MS2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant amino acid sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.
Catalog #A0858-98D
Cellular Localization Cell Membrane
ApplicationsSuitable for use in RIA, Immunofluorescence, Flow Cytometry, Direct ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1.0-3.0ug/ml. ~ 90kD band seen in Human Brain lysate.
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide QRKQGAGAPTAP, representing the C-Terminus of the human protein (residues 813-824), according to NP_001100.
SpecificitySpecies Crossreactivity: Crossreacts with Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCD156a antigen, Human Leukocyte Differentiation Antigen, Macrophage Cysteine Rich Glycoprotein


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