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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM8 (Disintegrin and Metalloproteinase Domain-containing Protein 8, ADAM 8, Cell Surface Antigen MS2, CD156a, MS2)

Anti -ADAM8 (Disintegrin and Metalloproteinase Domain-containing Protein 8, ADAM 8, Cell
Surface Antigen MS2, CD156a, MS2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Members of ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. The extracellular region of ADAM8 shows significant aa sequence homology to hemorrhagic snake venom proteins, including the metalloprotease and disintegrin domains. The expression of ADAM8 is upregulated by retinoic acid and vitamin D3. ADAM8 is involved in protein processing at the cell surface and is also thought to act as a leukocyte differentiation marker.
Catalog #A0858-98P
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:3000
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.0, 1% BSA, 0.01% thimerosal, 20% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa763-824 of human CD156.
SpecificityRecognizes human ADAM8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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