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Anti -ADAM15 (Metargidin, Metalloprotease RGD Disintegrin Protein, Metalloproteinase-like, Disintegrin-like, And Cysteine-rich Protein 15, MDC-15, Disintegrin and Metalloproteinase Domain-containing Protein 15, ADAM 15, MDC15)
Anti -ADAM15 (Metargidin, Metalloprotease RGD Disintegrin Protein, Metalloproteinase-like,
Disintegrin-like, And Cysteine-rich Protein 15, MDC-15, Disintegrin and Metalloproteinase
Domain-containing Protein 15, ADAM 15, MDC15)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, the protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. | | | Catalog # | A0859-31E | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:3000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, pH 7.0, 0.01% thimerosal, 10% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to human ADAM15. | | Specificity | Recognizes human ADAM15. Species sequence homology: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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