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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM15 (Metargidin, Metalloprotease RGD Disintegrin Protein, Metalloproteinase-like, Disintegrin-like, And Cysteine-rich Protein 15, MDC-15, Disintegrin and Metalloproteinase Domain-containing Protein 15, ADAM 15, MDC15)

Anti -ADAM15 (Metargidin, Metalloprotease RGD Disintegrin Protein, Metalloproteinase-like,
Disintegrin-like, And Cysteine-rich Protein 15, MDC-15, Disintegrin and Metalloproteinase
Domain-containing Protein 15, ADAM 15, MDC15)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, the protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.
Catalog #A0859-31E
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:3000
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.0, 0.01% thimerosal, 10% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human ADAM15.
SpecificityRecognizes human ADAM15. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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