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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM 17, CT (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)

Anti -ADAM 17, CT (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE,
TNF alpha Converting Enzyme, CD156b)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
ADAM-17, which is also known as CD156b, is expressed in a wide range of cells in culture. Its biological role is to convert the transmembrane trimeric form of TNF alpha to the soluble form. CD156 is also reported to process a number of other proteins, including L-selectin and TNF p75 receptor.
Catalog #A0859-35B
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:500
Optimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. m
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenPeptide corresponding to aa 807-823 of human CD156b
SpecificityRecognizes the C-terminal region of the TNF alpha converting enzyme (TACE), designated CD156b at the 6th leukocyte typing workshop. TACE is a membrane-bound metalloprotease disintegrin which belongs to the mammalian ADAM family.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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