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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)

Anti -ADAM 17, Propeptide Domain (A Disintegrin And Metalloproteinase 17, TNF-a Converting
Enzyme, TACE, TNF alpha Converting Enzyme, CD156b)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP
TACE (TNF-alpha converting enzyme) protein is a membrane bound matalloprotease from ADAM (a disintegrin and metalloprotease) family of proteins. It cleaves 26kD type II membrane-bound precursor of TNF-a into 17kD mature form which is secreted. TACE is also known to process other membrane proteins including TNF receptor, TGFa, L-selectin and amyloid protein precursor.
Catalog #A0859-35G
Epitope C-terminal
ApplicationsWestern Blot: (Ab 5ug/ml for 2 hrs at RT)
Immunoprecipitation: (Denatured verified) (Use Protein A) (Ab 10ug/mg protein lysate)
Positive Control HeLa cells
Cellular Localization Cell membrane
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenA synthetic peptide from the C-terminus of human TACE protein.
SpecificityRecognizes TACE. Species Crossreactivity: Human, Mouse and Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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