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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM 22 (A Disintegrin And Metalloproteinase 22)

Anti -ADAM 22 (A Disintegrin And Metalloproteinase 22)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP
Human ADAM22 is a member of the ADAM (a disintegrin and metalloprotease domain)
family of metalloproteases. Members of this family are membrane-anchored proteins
structurally related to snake venom disintegrins. They have been implicated in a variety of
biological processes involving cell-cell and cell-matrix interactions, such as fertilization,
muscle development, and neurogenesis. ADAM22 is highly expressed in the brain and may
function as an integrin ligand in the brain. The amino acid sequence of human ADAM22 is
100%, 96% and 92% identical to that of chimpanzee, dog and mouse.
Catalog #A0859-40J
ApplicationsSuitable for use in ELISA, Western Blot, and Immunoprecipitation. Other applications not tested.
Recommended DilutionELISA: 0.5-1.0ug/ml
Western Blot: 1-2ug/ml
Immunoprecipitation: 25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No9H36
HostMouse
SourceHuman
Concentration~500ug/ml
FormSupplied as a lyophilized powder in PBS, pH 7.2, 0.1% sodium azide. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenCHO-derived, recombinant human ADAM22 aa26-528; Q9POK1.
SpecificityRecognizes human ADAM22.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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