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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAM 22 (A Disintegrin And Metalloproteinase 22)

Anti -ADAM 22 (A Disintegrin And Metalloproteinase 22)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IP IH IF
ADAM 22 belongs to the ADAM gene family which have been shown to bind integrin and therefore may have a part in cell to cell or cell to matrix interactions. ADAM 22 is unique in the fact that it is only observed in the nervous system and predominantly in the brain. ADAM 22 is attached by cytoskeletal scaffolds to the postsynaptic density and is a receptor for LGI1.
Catalog #A0859-40K
ApplicationsSuitable for use in Immunoprecipitation, Immunohistochemistry and Immunofluorescence. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry: 1:400 detected ADAM 22 in rat myelinated neurite tissue.
Immunohistochemistry (Parafiin): 1:400 detected ADAM 22 in neurons/myelin in putamen area. Heat-induces epitope retrieval in citrate buffer pH 6.0 is recommended.
Western Blot: Detect ADAM 22 in rat and mouse brain tissue lystaes.
Optimal dilutions to be determined by the researcher.
Positive ControlRat myelinated neurite tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No11C229
HostMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to mouse ADAM 22 at the cytoplasmic domain.
SpecificityRecognizes ADAM22 at the cytoplasmic domain. Species crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesADAM metallopeptidase domain 22 Metalloproteinase-disintegrin ADAM22-3 a disintegrin and metalloproteinase domain 22 disintegrin and metalloproteinase domain-containing protein 22Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2


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