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You are here:Home » Antibodies » Abs to Proteins » Anti -ADAP (SLAP-130, Fyb)

Anti -ADAP (SLAP-130, Fyb)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Human SH2 domain containing leukocyte protein-76-Associated Phosphoprotein of 130kD (SLAP-130), also known as Fyb-120 and ADAP, is an 86kD, 783 amino acid, cytoplasmic protein that runs anomalously as a 120-130kD protein in SDS-PAGE. Human SLAP-130 is a hematopoietic-specific adaptor that associates with other cytoplasmic proteins such as SH2-containing Leukocyte Phosphoprotein of 76kD (SLP-76). Adaptors integrate signals from surface receptors and are essential components of many immune cell-signaling cascades. There is at least one known alternatively spliced SLAP-130 isoform which contains an additional 46 aa. Over the region used as immunogen, SLAP-130 is 66% and 76% identical to the corresponding canine and mouse proteins, respectively.
Catalog #A0859-43C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, PBS, 01% sodium azide. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG3
Clone No8H202
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with 100ul 40-50% glycerol, PBS, 01% sodium azide.
PurityPurified by Protein G chromatography.
ImmunogenRecombinant human SLAP-130 aa 2-274 (E. coli).
SpecificityRecognizes human SLAP-130.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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