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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAMTSL-1 (Punctin (Aggrecanase I, A Disintegrin And Metalloproteinase with ThromboSpondin-3 motif)

Anti -ADAMTSL-1 (Punctin (Aggrecanase I, A Disintegrin And Metalloproteinase with
ThromboSpondin-3 motif)


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Clone Host Grade Applications
Monoclonal Mouse Purified B
Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an “aggrecanase.” Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains.
Catalog #A0859-62
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:250-1:500
Human muscle cell lysate may be used as a positive control and an approximately 60kD band will be detected.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No4H19
ConcentrationNot determined
FormSupplied as a liquid in PBS, 0.02% sodium azide.
ImmunogenSynthetic peptide containing amino acid residues of human punctin protein.
SpecificityRecognizes human ADAMTSL-1 (Punctin (Aggrecanase I, A Disintigrin And Metalloproteinase with ThromboSpondin-3 motif))
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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