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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -ADAMTSL1 (Punctin-1, ADAMTS-like Protein 1, ADAMTSL-1, ADAMTSR1, C9orf94, UNQ528/PRO1071)

Anti -ADAMTSL1 (Punctin-1, ADAMTS-like Protein 1, ADAMTSL-1, ADAMTSR1, C9orf94,
UNQ528/PRO1071)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Punctin-1 is a secreted molecule resembling members of the family of proteases designated ADAMTS (a disintegrin-like and metalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes that consist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (which provide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including 4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into the cell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2 (ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to have important functions in the extracellular matrix. This monoclonal antibody recognizes the spacer domain and reacts with molecular species of 55kD or a doublet of 55kD and 60kD (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.
Catalog #A0859-62D
ApplicationsSuitable for use in Western Blot and ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No13A15
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to human Punctin-1.
SpecificityRecognizes human Punctin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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