| Hexon protein is a major coat protein of adenoviruses. Adenoviruses capsids have three principal protein components: the hexon, the penton, and the fiber. Hexon consists of three subunits together forming two major components of different morphological symmetry. A triangular top with three towers of density is superimposed on a more bulky pseudo hexagonal base. The symmetry of the top is in accord with the trimeric nature of hexon, but that of the base derives from the molecular function, which is to provide a densely packed impenetrable protective outer layer for the virion. |
|
| Catalog # | A0880-04M |
| Applications | Suitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested. |
| Recommended Dilution | ELISA: 1:5000 |
| Western Blot: 1:1000 |
| Immunofluorescence: 1:8000 |
| Optimal dilutions to be determined by the researcher. |
| Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Isotype | IgG |
| Host | Goat |
| Concentration | ~1mg/ml |
| Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin. |
| Purity | Purified |
| Immunogen | Gradient purified, disrupted Adenovirus type 5 virions. |
| Specificity | Recognizes numerous Adeno proteins including hexon protein. Reacts with Adenovirus types 1, 2, 3, 5, 6, 7a, 8, 31, 40 and 41. Broad reactivity with other Adenovirus types is expected. |
| This antibody does not crossreact with Parainfluenza types 1-3, |
| Influenza A & B, RSV, human MPV and Rhinovirus type |
| 16. It does not react with uninfected Hep2, LLCMK2 and Vero cells. |
|
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |