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You are here:Home » Antibodies » Abs to Enzymes, Phospholipase » Anti -ATGL (Patatin-like Phospholipase Domain-containing Protein 2, Adipose Triglyceride Lipase, Calcium-independent Phospholipase A2, Desnutrin, IPLA2-zeta, Pigment Epithelium-derived Factor, TTS2.2, Transport-secretion Protein 2, TTS2, PNPLA2, ATGL, FP17548)

Anti -ATGL (Patatin-like Phospholipase Domain-containing Protein 2, Adipose Triglyceride
Lipase, Calcium-independent Phospholipase A2, Desnutrin, IPLA2-zeta, Pigment
Epithelium-derived Factor, TTS2.2, Transport-secretion Protein 2, TTS2, PNPLA2, ATGL,
FP17548)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Triglycerides are the most efficient form of energy storage in mammalian adipose tissue during times of caloric excess. ATGL is one of the key enzymes involved in the mobilization of fatty acids from triglyceride stores in adipose tissue, catalyzing the conversion of triacylglycerols to diacylglycerols. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity, and thus may be a potential drug target for the diabetic pathology. ATGL mRNA is detected in a wide range of tissues including adipose, lung, skeletal muscle, testis, heart, brain, and kidney, with adipose tissue expressing the highest level.
Catalog #A0888-35G
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.5-2ug/ml, observed in human adipose, heart and testis lysates on ~60kD bands
Immunohistochemistry (Paraffin): 2-3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-NIIEVSKEARKR, from human PNPLA2, at the internal region of the protein (NP_065109.1).
SpecificityRecognizes human PNPLA2. Species sequence homology: Bovine, canine, mouse, porcine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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