Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -Adiponectin (Acrp30, Adipocyte Complement-related Protein of 30kD, AdipoQ, apM1, Gelatin Binding Protein 28, GPB28)

Anti -Adiponectin (Acrp30, Adipocyte Complement-related Protein of 30kD, AdipoQ, apM1,
Gelatin Binding Protein 28, GPB28)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 amino acid protein, the product of the apM1 gene which is physiologically active and specifically and highly expressed in adipose cells (adipokine).
The protein belongs to the soluble defence collagen superfamily. It has a collagen-like domain which is structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. Adiponectin forms homotrimers, which are the building blocks for higher-order complexes found circulating in serum. A reduction in adiponectin serum levels is accompanied by insulin resistance states such as obesity and type 2 diabetes mellitus. It is also reported in patients with coronary artery disease. Increased adiponectin levels are associated with type 1 diabetes mellitus, anorexia nervosa and chronic renal failure.
Adiponectin has been shown to increase insulin sensitivity and decrease plasma glucose by increasing tissue fat oxidation. It inhibits the inflammatory processes of atherosclerosis suppressing the expression of adhesion and cytokine molecules in vascular endothelial cells and macrophages, respectively.
Catalog #A0891-01
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionIndirect ELISA: >1:100,000 using 2.5ng of antigen coated per well
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
IsotypeIgG
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder in PBS, pH 7.2
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman adiponectin (His-tagged fusion protein) from E. coli.
SpecificityRecombinant human adiponectin is 100% homologous with the human serum adiponectin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links