Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Enzymes, Phospholipase » Anti -ADPN (Adiponutrin, Patatin-like Phospholipase Domain containing 3)

Anti -ADPN (Adiponutrin, Patatin-like Phospholipase Domain containing 3)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
PPNPLA3(patatin-like phospholipase domain-containing protein 3), also named as ADPN, C22orf20, alternatively referred to as adiponutrin, encodes a 481-amino acid protein of 54 kD that belongs to the patatin-like phospholipase domain-containing family. Despite the apparent absence of a membrane-spanning domain, PNPLA3 is tightly associated with membranes and it may be targeted specifically to regions of the ER membrane that are destined to become nascent lipid droplets (PMID:22338072). It is a multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. Genetic variations in PNPLA3 are a cause of susceptibility to non-alcoholic fatty liver disease type 1 (NAFLD1). It has 2 isoforms produced by alternative splicing
Catalog #A0901-25
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:200-1:1000
Optimal dilution determined by the researcher
Positive ControlsHepG2 cells, human adipose tissue and Jurkat cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.3, 0.1% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenPNPLA3 fusion protein ag1959
SpecificityRecognizes human ADPN at ~53kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links