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You are here:Home » Antibodies » Abs to Enzymes, Synthase » Anti -ALAD, CT (Delta-aminolevulinic Acid Dehydratase, ALADH, Porphobilinogen Synthase)

Anti -ALAD, CT (Delta-aminolevulinic Acid Dehydratase, ALADH, Porphobilinogen Synthase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IH FC
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Catalog #A0903-10
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Flow Cytometry Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide between corresponding to a portion of amino acids within aa251-280 from the C-terminal region of human ALAD, KLH conjugated (P13716).
SpecificityRecognizes human ALAD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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