| Catalog # | A0906-80C |
| The alpha-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. There are 3 highly homologous subtypes | alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Alpha2C is required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. |
| Positive Control | Human brain lysate and rat ventral spinal cord |
| Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. |
| Recommended Dilution | Optimal dilutions to be determined by the researcher. |
| Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| CAS Number | n/a |
| Clone Type | Polyclonal |
| Host | Rabbit |
| Source | Human |
| Concentration | ~1mg/ml |
| Form | Supplied as a liquid in PBS, pH 7.2. |
| Purity | Purified by immunoaffinity chromatography. |
| Immunogen | Synthetic peptide comprising residues 309-324 [GAEGGAGGADGQGAGP] of the human Alpha 2c protein. |
| Specificity | Recognizes human Adrenergic Receptor, alpha 2c. |
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| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
| Alternate names | ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR, Alpha2-AR-C4, Alpha-2-adrenergic receptor, renal type, adrenergic, alpha-2C-, receptor, alpha-2C-adrenergic receptor |
