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You are here:Home » Antibodies » Abs to Receptors » Anti -Adrenergic Receptor, beta 2 (B2AR)

Anti -Adrenergic Receptor, beta 2 (B2AR)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified B IH
b2-Adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Catalog #A0906-88B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000
Immunohistochemistry: 1:200
Optimal dilutions to be determined by the researcher.
Recommended Secondary AntibodiesI1906: IgY, Chicken Pab Rb x Ch
I1906-10: IgY, Chicken (HRP) Rb x Ch
I1906-12: IgY, Chicken (FITC) Rb x Ch
I1906-14: IgY, Chicken (AP) Rb x Ch
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenRecombinant protein corresponding to aa335-408, DFRIAFQELLC LRRSSLKAYGN GYSSNGNTGE QSGYHVEQEKE NKLLCEDLPGT EDFVGHQGTVP SDNIDSQGRNCS T, of human beta 2 Adrenergic Receptor (NP_000015.1). Cellular Localization: Cell Membrane
SpecificityRecognizes human Beta 2 Andrenergic Receptor at ~46.5kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesADRB2, Adrenergic, beta-2-, Receptor, Surface [Homo sapiens], HGNC:286, ADRB2R, ADRBR, BAR, BETA2AR, beta-2 Adrenergic Receptor, beta-2 Adrenoceptor, Catecholamine Receptor


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