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You are here:Home » Antibodies » Abs to Hormones, Steroids » Anti -ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

Anti -ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease.
Catalog #A0909
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin/paraffin): 0.2-0.4ug/ml. Incubate 30 minutes at RT. No special pretreatment required for staining.
Optimal dilutions to be determined by the researcher.
Positive Control
Normal pituitary glad or pituitary adenoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No0.N.10
HostMouse
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 15mM sodium azide. Also available without BSA and azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-24 from the N-terminal of human ACTH. Cellular Localization: Cytoplasmic
SpecificityRecognizes human Adrenocorticotrophic Hormone (ACTH). Shows broad species crossreactivity.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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