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You are here:Home » Antibodies » Abs to Proteins » Anti -Adrenoleukodystrophy Protein (ALDP)

Anti -Adrenoleukodystrophy Protein (ALDP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IH IC
Catalog #A0909-25B
ELISA 1:500–1:5,000 Immunoblotting: 1:500–1:5,000 Immunohistochemistry: 1:500–1:5,000 Immunocytochemistry: 1:500–1:5,000
Can be used to analyze ALDP protein in cells and tissues from normal individuals, or from patients with adrenoleukodystrophy (ALD) or Zellweger syndrome and related peroxisomal diseases, and provides an excellent marker for peroxisomes (Mosser et al. 1994). About 70% of ALD male patients have no detectable ALDP in fibroblasts or leukocytes. A similar proportion of carrier females may show mosaïcism for the presence or absence of ALDP.
CAS Numbern/a
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q5
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as liquid ascites without preservative.
PurityAscites
ImmunogenALDP1 fragment from aa 279 to 482 as a fusion protein
SpecificityHuman ALDP. No crossreactivity with mouse ALDRP, PMP70. Crossreactivity to an unidentified 80kD MW protein is present in lymphoblastoid cells, but not in several other cells or tissues tested.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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