Adrenomedullin, aa1-6

Clone Type

Polyclonal

Host

Guinea pig

Source

Rat

Isotype

IgG

Grade

Serum

Applications

IHC

Crossreactivity

Shipping Temp

Blue Ice

Storage Temp

-20°C

Adrenomedullin is a potent vasorelaxing and hypotensive peptide, originally isolated from human pheochromocytoma. Adrenomedullin shares some homology with CGRP (calcitonin gene-related peptide).

Applications

Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution

Immunohistochemistry (Frozen): 1:400-1:800 Optimal dilutions to be determined by the researcher.

Positive Control

Stefanini-fixed frozen sections of rat fundus.

Storage and Stability

Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunogen

Synthetic peptide corresponding to aa1-6 from rat adrenomedullin, conjugated to BSA.

Form

Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.

Purity

Serum.

Specificity

Recognizes rat Adrenomedullin. Does not crossreact with CGRP.

References

1. Mulder H. et al.: Adrenomedullin, localization in the gastrointestinal tract and effects on insulin secretion. Regulatory Peptides 62, 107-112 (1996).