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You are here:Home » Antibodies » Abs to Toxins » Anti -Aflatoxin B, pan

Anti -Aflatoxin B, pan

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Aflatoxin is a potent carcinogen. The fungus, genus Aspergillus, that secretes aflatoxin enters the plant usually through the wounds left by an insect pest, since most plants have a hard outer layer that acts as a barrier to fungi. Once inside the plant, the fungus can reach all parts of the plant, including its seeds. Aflatoxin is a serious cause of illness and death in developing countries which have fewer food safety regulations. Some plant scientists are trying to develop transgenic corn with a gene for an enzyme which breaks down aflatoxin.
Catalog #A0925-01
Aflatoxin is listed as a possible carcinogen, and has been shown to cause liver damage, some of which may be cumulative,  in many mammals that ingest sufficient quantities of it, though tolerance seems to vary by species.  In most species, aflatoxin cannot be detected in the liver 14 days after it has been withdrawn from the animals diet, though some of its effects may still be present.  Animals affected by aflatoxicosis show reduced feed intake, and even mortality, if sufficient amounts of aflatoxin are ingested for a sufficient period of time.  Sensitivity, however, seems to vary not only by species, but also by individual animals.
Affinity Constant ~6.6x10e9L/M
Applications Suitable for use in ELISA and Binding assays. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No2F10
HostMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenAflatoxin B
SpecificityReactive to all isoforms ofAflatoxin B
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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