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A0925-01E Rat Anti-Aflatoxin M1, B1 (AFM1, AFB1) (Glycerol Free)

Specifications
Clone Type
Monoclonal
Host
Rat
Source
Rat
Isotype
IgG2b
Clone Number
3H57 (IC6)
Grade
Affinity Purified
Applications
E
Crossreactivity
Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C

Aflatoxin is a potent carcinogen. The fungus, genus Aspergillus, that secretes aflatoxin enters the plant usually through the wounds left by an insect pest, since most plants have a hard outer layer that acts as a barrier to fungi. Once inside the plant, the fungus can reach all parts of the plant, including its seeds. Aflatoxin is a serious cause of illness and death in developing countries which have fewer food safety regulations. Some plant scientists are trying to develop transgenic corn with a gene for an enzyme which breaks down aflatoxin. Aflatoxin is listed as a possible carcinogen, and has been shown to cause liver damage, some of which may be cumulative, in many mammals that ingest sufficient quantities of it, though tolerance seems to vary by species. In most species, aflatoxin cannot be detected in the liver 14 days after it has been withdrawn from the animals diet, though some of its effects may still be present. Animals affected by aflatoxicosis show reduced feed intake, and even mortality, if sufficient amounts of aflatoxin are ingested for a sufficient period of time. Sensitivity, however, seems to vary not only by species, but also by individual animals.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Wistar rats were immunized with Aflatoxin M1-BSA conjugate
Form
Supplied as a liquid in PBS, pH 7.2.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes Aflatoxin M1 (AFM1) and Aflatoxin B1 (AFB1), but not reactive to BSA or other irrelevant antigens by ELISA.
Conjugates
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