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You are here:Home » Antibodies » Abs to Toxins » Anti -Aflatoxin M1, B1 (AFM1, AFB1) (Glycerol Free)

Anti -Aflatoxin M1, B1 (AFM1, AFB1) (Glycerol Free)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E
Aflatoxin is a potent carcinogen. The fungus, genus Aspergillus, that secretes aflatoxin enters the plant usually through the wounds left by an insect pest, since most plants have a hard outer layer that acts as a barrier to fungi. Once inside the plant, the fungus can reach all parts of the plant, including its seeds. Aflatoxin is a serious cause of illness and death in developing countries which have fewer food safety regulations. Some plant scientists are trying to develop transgenic corn with a gene for an enzyme which breaks down aflatoxin. Aflatoxin is listed as a possible carcinogen, and has been shown to cause liver damage, some of which may be cumulative, in many mammals that ingest sufficient quantities of it, though tolerance seems to vary by species.  In most species, aflatoxin cannot be detected in the liver 14 days after it has been withdrawn from the animals diet, though some of its effects may still be present.  Animals affected by aflatoxicosis show reduced feed intake, and even mortality, if sufficient amounts of aflatoxin are ingested for a sufficient period of time.  Sensitivity, however, seems to vary not only by species, but also by individual animals.
Catalog #A0925-01E
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No3H57
HostRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenWistar rats were immunized with Aflatoxin M1-BSA conjugate
SpecificityRecognizes Aflatoxin M1 (AFM1) and Aflatoxin B1 (AFB1), but not reactive to BSA or other irrelevant antigens by ELISA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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