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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -AFX, phosphorylated (Ser197) (Forkhead Box Protein O4, Fork Head Domain Transcription Factor AFX1, FOXO4, AFX1, MLLT7)

Anti -AFX, phosphorylated (Ser197) (Forkhead Box Protein O4, Fork Head Domain
Transcription Factor AFX1, FOXO4, AFX1, MLLT7)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Several studies indicate that FKHR and AFX, mammalian homologues of the Caenorhabditis elegans forkhead transcription factor DAF-16, function in the insulin signaling pathway promoter contains one IRS, while in the IGFBP-1 promoter two copies of IRS are arranged as an inverted palindrome. Three tandem copies of IRSs are present in the G6Pase. AFX has been recently shown to serve as a substrate of PKB both in vitro and in vivo, and its transcriptional activity is inhibited by phosphorylation.
Catalog #A0928-02A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot:1:500-1:1,000
Immunohistochemistry:1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
ConcentrationAs reported
FormSupplied as a liquid.
PurityPurified by immunoaffinity chromatography.
ImmunogenAFX, phosphorylated (Ser197).
SpecificityRecognizes AFX, phosphorylated at (Ser197). Species Cross-Reactivity: human, mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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