Anti -Aggrecan (Proteoglycan, PG, AGC 1, Aggrecan 1, Antigen Identified By Monoclonal
A0122, Cartilage Specific Proteoglycan Core Protein, Chondroitin Sulfate Proteoglycan Core
Protein 1, CSPCP, CSPG1, CSPGCP, Large Aggregating Proteoglycan, MSK16, SEDK)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
E B IP IH |
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| Aggrecan is a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. | | | Catalog # | A1059-53E | | Applications | Suitable for use in Immunohistochemistry, ELISA, Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: Frozen and paraffin sections. | | Optimal working dilutions to be determined by researcher. | | Recommended Secondary Reagents | I1904-19C: IgG, F(ab’)2 (HRP) Pab Gt x Mo | | Positive Control | Cerebral Cortex | | Hybridoma | NS1 myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 3H525 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.2M Tris-HCl, pH 7.4, 5-10% fetal calf serum, 0.09% sodium azide. | | Purity | Supernatant | | Immunogen | Purified human articlular cartilage aggrecan. | | Specificity | Recognizes human aggrecan. Recognizes epitopes within the N-terminal G1-IGD-G2 region of aggrecan that has been identified as cluster 1 isoform. Species Crossreactivity: Bovine. Does not react with chicken, fish or rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Aggrecan (Proteoglycan, PG, AGC 1, Aggrecan 1, Antigen Identified By Monoclonal A0122, Cartilage Specific Proteoglycan Core Protein, Chondroitin Sulfate Proteoglycan Core Protein 1, CSPCP, CSPG1, CSPGCP, Large Aggregating Proteoglycan, MSK16, SEDK) |
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