Anti -AGPAT6 (1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, Testis spermatogenesis
apoptosis-related protein 7, EC=2.3.1.51, 1-AGP acyltransferase 6, 1-AGPAT 6,
Lysophosphatidic acid acyltransferase-zeta, LPAAT-zeta)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| AGPAT6 is a novel glycerolipid acyltransferase of the ER, which is crucial for the production of milk fat by the mammary gland. | | | Agpat6 deficient mice exhibit a 25% reduction in body weight and resistance to both diet-induced and genetically induced obesity. The reduced body weight is associated with increased energy expenditure, reduced triglyceride accumulation in BAT and WAT, reduced white adipocyte size, and lack of adipose tissue in the subdermal region. AGPAT6 plays a unique role in determining triglyceride content and composition in adipose tissue and liver that cannot be compensated by other members of the Agpat family. (1) | | | Catalog # | A1059-59C | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 2ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Mouse skeletal muscle lysate | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2, 0.05% sodium azide. | | Purity | Purified by peptide immunoaffinity chromatography. | | Immunogen | A synthetic peptide made to an N-terminal portion of the human AGPAT6 protein sequence (between residues 1-100). [Swiss-Prot Q86UL3]. Cellular Localization: membrane | | Specificity | Recognizes human AGPAT6 at ~58kD. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta, Testis spermatogenesis apoptosis-related protein 7, EC=2.3.1.51, 1-AGP acyltransferase 6, 1-AGPAT 6, Lysophosphatidic acid acyltransferase-zeta, LPAAT-zeta |
External Links
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