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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -AHA1 (Activator of Hsp90 ATPase 1)

Anti -AHA1 (Activator of Hsp90 ATPase 1)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B IP IH IC IF
Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3).
Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
Catalog #A1059-69D
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot:1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a/Kappa
Clone No10F681
HostRat
SourceMouse
Concentration~1.59mg/ml
FormSupplied as a liquid in 0.02M potassium phosphate, 0.15M Sodium chloride pH7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenMouse Aha1.
SpecificityRecognizes Mouse Aha1. Species Crossreactivity: human,
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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