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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -AHI1 (Jouberin, Abelson Helper Integration Site 1 Protein Homolog, AHI-1)

Anti -AHI1 (Jouberin, Abelson Helper Integration Site 1 Protein Homolog, AHI-1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
AHI1, encoding the Jouberin protein, is an alternatively spliced signaling molecule that contains seven Trp-Asp (WD) repeats, an SH3 domain, and numerous SH3-binding sites. The gene is expressed strongly in embryonic hindbrain and forebrain, and AHI1 may be required for both cerebellar and cortical development in humans. Defects in AHI1 are the cause of Joubert syndrome 3, an autosomal recessive brain congenital malformation. The exact function of the AHI1 gene is not yet known.
Catalog #A1059-71C
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to PTAESEAKVKTC, from AHI1, at N-terminal (NP_060121.3, NP_001128303.1).
SpecificityRecognizes AHI1. Species sequence homology: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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