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Abs to Apoptosis
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Anti -AIF (Apoptosis-inducing Factor 1 Mitochondrial, Apoptosis-inducing Factor Mitochondrion-associated 1, AIFM1, COXPD6, MGC111425, Programmed Cell Death Protein 8, PDCD8)
Anti -AIF (Apoptosis-inducing Factor 1 Mitochondrial, Apoptosis-inducing Factor Mitochondrion-associated 1, AIFM1, COXPD6, MGC111425, Programmed Cell Death Protein 8, PDCD8)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Apoptosis-inducing factor (AIF) is a phylogenetically ancient mitochondrial intermembrane flavoprotein. AIF induces caspase-independent peripheral chromatin condensation and large-scale DNA fragmentation when added to purified nuclei. Upon apoptosis induction AIF translocates to the cytosol and the nucleus. | | | Catalog # | A1059-78T | | Applications | Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 0.25-1µg/ml | | Western Blot: 0.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human, mouse, rat heart lysate, or K562 cell lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to human AIF. | | Specificity | Recognizes human AIF. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=1.-.-.- |
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