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You are here:Home » Antibodies » Abs to Neuroscience » Anti -AIP1 (Atrophin-1-interacting Protein 1, Atrophin-1-interacting Protein A, Membrane-associated Guanylate Kinase, WW and PDZ Domain-containing Protein 2, Membrane-associated Guanylate Kinase Inverted 2, MAGI-2)

Anti -AIP1 (Atrophin-1-interacting Protein 1, Atrophin-1-interacting Protein A,
Membrane-associated Guanylate Kinase, WW and PDZ Domain-containing Protein 2,
Membrane-associated Guanylate Kinase Inverted 2, MAGI-2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Atrophin-1 (AIP1) contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. This protein is brain specific, where it appears to be widely expressed in both neurons and glia.
Catalog #A1059-87J
Application(s)
ELISA, Western Blot: No signal obtained yet but a preliminary experiment showed low background in Human Brain extract at up to 1ug/ml. Other applications not tested.
Recommended DilutionELISA: > 1:32,000
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS NumberN/A
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified from goat serum by ammonium sulfate precipitation followed by immunoaffinity chromatography using the immunizing peptide.
ImmunogenPeptide with sequence PSVLKPGASAASR, from C Terminus of the protein sequence according to NP_036433.
SpecificityRecognizes AIP1. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAtrophin-1-interacting Protein 1, Atrophin-1-interacting Protein A, Membrane-associated Guanylate Kinase, WW and PDZ Domain-containing Protein 2, Membrane-associated Guanylate Kinase Inverted 2, MAGI-2


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