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Anti -AIRE (APECED, APS1, APSI, Autoimmune Regulator, PGA1, Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Protein)
Anti -AIRE (APECED, APS1, APSI, Autoimmune Regulator, PGA1, Autoimmune Polyendocrinopathy
Candidiasis Ectodermal Dystrophy Protein)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). | | | Catalog # | A1059-88A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:64,000. | | Western Blot: 0.3-1ug/ml. ~ 55kDa band observed in Human Spleen lysates (calculated MW of 57.7kDa according to NP_000374.1). | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | | | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide, C-KAKPPKKPESSAEQ, representing the internal region of the human protein according to NP_000374.1; NP_000649.1. Homology | | Specificity | Species Crossreactivity: Human. Other species not tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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